C3 or Not C3: That Is the Question

C3 or not C3: that is the question.

Numerous investigators have studied the potential genetic causes of essential hypertension, and several genes have been described as candidates.1,2 These genes may contribute to the inappropriate and exaggerated growth of arterial smooth muscle cells in genetically hypertensive individuals and thus ultimately contribute to the disease by supporting creation of stronger, more muscular, and somet...

Frail or not? That is the question.

coeliac disease: to classify or not to classify – that is the question!

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To scavenge or not to scavenge: that is the question.

Analysis of a series of diffraction data sets measured from four native as well as four nicotinic acid-soaked crystals of trypsin at 100 K shows a high variability in radiation-sensitivity among individual crystals for both nicotinic acid-soaked and native crystals. The level of radiation-sensitivity and the extent of its variability is statistically indistinguishable between the two conditions...

To P or not to P: that is the question.

In 1993 Eugene Harris, a well-known biostatistician at the NIH, wrote an editorial for Clinical Chemistry regarding the use of P values vs confidence intervals in the evaluation of scientific data (1 ). This has long been a contentious topic in the scientific world and one with which each new generation of scientists has had to grapple on the basis of arguments advanced for the use of various s...